Profhilo® London

Clinic in Harley Street

Unrivalled quality with natural, long-lasting results

Profhilo® is a revolutionary, injectable skin remodelling system that uses the highest-grade hyaluronic acid formulations to replenish and revitalise the skin tissues to reduce lines, wrinkles and skin sagging. This state-of-the-art treatment, known as ‘liquid skincare’ is now available at The Harley Street Filler Specialist London.

What is Profhilo®?

Known as skin bio-remodelling, Profhilo® is not like a traditional dermal filler as it will not physically augment the skin or sculpt certain facial features. Rather, it speaks with the skin on a cellular level and integrates with the underlying tissues to communicate with the skin cells for repair and restoration.

It can address the entire facial area and helps to replenish lost hyaluronic acid, which depletes as we age. In addition, Profhilo® stimulates collagen and elastin; vital for a plump and youthful complexion.

The injections are made just beneath the skin’s surface and in the days that follow, the product disperses across a wider area of skin tissues. As it integrates into the skin layers, the magic starts to happen.

In a course of 2 treatments, 4 weeks apart, you will notice your skin become more plump and hydrated. Lines and wrinkles can fade and you’ll be left with a radiant glow. Profhilo® can also be used in conjunction with other injectables, such as Botox® and dermal fillers, for a truly holistic approach to skin ageing.

Why have a treatment with Profhilo®?

If you are someone who is experiencing the first or advanced signs of ageing, you will know that the skin can feel dehydrated and lose its elasticity. Profhilo® is an injectable treatment that enables the skin to work from the inside, to replenish and heal itself.

Unlike a traditional dermal filler, Profhilo® can work across the skin’s architecture in an overall facial and neck treatment to bring life back to the skin and offer a more youthful and rejuvenated look and feel.

Which dermatological conditions can Profhilo® treat?

  • Fine lines and deeper wrinkles
  • Dryness and dehydrated skin
  • Loss of elasticity (sagging)
  • Loss of volume in hollow areas such as the lower cheeks
  • A dull or uneven skin tone and texture
  • Crêpey skin (perfect for hands and elbows)

Frequently asked questions about Profhilo®

Am I suitable for a treatment with Profhilo® at The Harley Street Face Clinic?

If you are experiencing both mild and more advanced skin ageing, the likelihood will be that you could benefit from the skin rejuvenating properties of a course of Profhilo®. However, we will always ask that you attend a no-obligation consultation, prior to any treatment being carried out, here at The Harley Street Face Clinic, London.

This meeting enables your practitioner to assess your individual facial concerns, check your medical history and answer any questions you might have about the Profhilo® treatment. Once this initial meeting has taken place and you are both happy to proceed, you can book your first treatment session.

What happens during a Profhilo® treatment?

After you have completed some standard consent forms, you will be asked to relax in one of our treatment rooms. Your skin will be cleansed and numbing cream applied. This takes around 30 minutes to take effect and will ensure your comfort throughout the treatment.

Once you are numb, your practitioner will inject the Profhilo® solution into several key areas of your face and/or neck. Once this is complete, you will be able to return to your daily activities with no clinical downtime.

Do Profhilo® injections hurt?

There can be some sensation with Profhilo® as we are using needles to apply the product to the skin. However, as a topical anaesthetic is applied before your Profhilo® injections, this will minimise any discomfort and will ensure that the treatment is not painful.

What results can I expect from Profhilo® treatment?

As Profhilo® is usually administered in a course of 2 sessions, 1 month apart for optimum results, you should start to see some results after 3 to 4 weeks and the full results at week 8.

Expect your skin to be more hydrated, toned and plump in both looks and feel. Fine lines can be reduced and your skin can appear smoother and more evenly textured. If you experience more advanced signs of skin ageing, another treatment, 6 months after the initial course, may be recommended for absolute optimum results.

Is there any downtime after Profhilo® treatment?

There is no ‘clinical’ downtime following Profhilo® treatment (meaning that you won’t need time to rest or recover at home). However, there may be some ‘cosmetic’ downtime, where you may notice small localized small bumps where the injections have been administered.

This is very normal and the lumps will subside as the product disperses, in around 24 hours. You might also experience a little swelling and slight bruising, where the needles have been applied to the skin. These reactions are all common and nothing to be concerned about.

How long will the results from my Profhilo® treatment last?

You can experience superb results, where your skin will look and feel more radiant and youthful, for up to 6 months. However, every patient responds differently to cosmetic treatments.

Certain lifestyle choices such as smoking, sun exposure, excessive cardiovascular exercise, a poor diet and consuming excessive amounts of alcohol could mean that you may need to return to the clinic sooner, for another treatment. If you maintain a good skincare regime and look after your general health, the results are more likely to last the maximum duration.

    Client Reviews

    "The procedure that I had with Dr De Silva went very well and I am happy with the results. Dr De Silva and his team spent a lot of time with me: they were good listeners and their answers gave me a lot of reassurance."


    "I always felt well looked after and I'm very happy with the results. The entire experience was premium from initial consultation to follow ups. I would recommend paying more to be confident in the safety of your procedure."


    "The whole process from start to finish has been outstanding. Dr Julian De Silva acted professionally from the outset, he listened very carefully to what I wanted and most importantly, delivered the best results I could have possibly asked for."



    23 Harley Street
    W1G 9QN , UK

    Call: 020 8016 6045


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    Dr Julian De Silva
    5 stars based on 458 reviews

    Renowned expert in Facial Cosmetic and Plastic Surgery. Signature techniques in Blepharoplasty, Rhinoplasty and Facelift surgery. Expert in revision surgery and in natural looking results